Women:

• Fatigue or low energy: Persistent tiredness or reduced stamina.
• Low mood or depression: Changes in emotional wellbeing or motivation.
• Reduced libido: Decline in sexual desire or interest.
• Premenstrual symptoms: PMS or cyclical symptom patterns.
• Menopausal transition: Menopause-related changes such as sleep disruption or hot flushes.
• Weight gain: Gradual or unexplained weight increase.

Men:

• Fatigue or low energy: Ongoing tiredness or reduced physical drive.
• Low mood or depression: Persistent low mood or reduced motivation.
• Reduced sex drive: Lower libido or changes in sexual interest.
• Sleep disturbance: Difficulty falling asleep or staying asleep.
• Hair loss: Thinning hair or changes in hair pattern.
• Weight gain: Increased abdominal or overall body weight.

Overview

DUTCH Adrenal measures adrenal-related hormones using dried urine samples collected across multiple time points in a single day. The test includes daily free cortisol and cortisone patterns, cortisol and cortisone metabolites, and DHEA-S, analysed using LC-MS/MS technology and normalised to creatinine.

These markers are included to provide a layered view of adrenal hormone activity across the day. Free cortisol and cortisone patterns offer insight into daily rhythm and timing, while metabolite measurements reflect overall hormone output. DHEA-S adds additional context around longer-term adrenal hormone production, supporting a more complete interpretation than single-marker testing alone.

Practitioners typically interpret DUTCH Adrenal results alongside symptom patterns, sleep-wake timing, lifestyle factors, stress exposure and other laboratory findings. Results are reviewed in context to understand how daily hormone patterns align with the individual experience of clients.

Practical

Sample Type:

Dried urine

Turnaround time:

Maximum of 21 days