• Lyme disease considerations: confirmed or suspected Lyme disease, or past Borrelia exposure.
• Persistent fatigue or low stamina: ongoing tiredness or reduced resilience.
• Neurological or cognitive concerns: sensory changes, nerve discomfort or cognitive fluctuations.
• Musculoskeletal symptoms: widespread aches or joint discomfort.
• Tick exposure history: known or suspected tick bites or time spent in tick-prevalent areas.
• Immune response considerations: atypical or inconsistent antibody patterns.
• Recurring viral-type presentations: cycles of malaise or flu-like experiences.
• Long-standing multi-system symptoms: persistent, unexplained patterns affecting several body systems.

Overview

The Borrelia Elispot test measures T-cell reactivity to Borrelia burgdorferi antigens, providing insight into cellular immune activity associated with Borrelia exposure. By identifying T-cell responses at a high analytical sensitivity, the test can offer additional context alongside antibody assessments and other immune markers.

Clinically, this assessment may be useful when exploring suspected or confirmed Lyme disease, long-lasting fatigue, neurological or musculoskeletal concerns, recurring viral-type experiences, a history of tick exposure or broader immune response patterns. Reviewing T-cell reactivity may help practitioners consider how cellular immune activity fits within the wider picture of a client’s presentation.

Practitioners typically interpret Borrelia Elispot results together with symptom history, exposure timelines, antibody results, lifestyle factors and environmental influences. Used in this way, the test can support a more comprehensive evaluation of immune-related patterns for clients.

Practical

ACD/CPDA

This sample requires a blood draw