- Cancer risk screening: Asymptomatic adults aged 40-70 seeking early tumour detection.
- Family history of cancer: Individuals with increased concern about inherited cancer risk.
- Preventive health assessment: Inclusion in routine wellness screening programmes.
- High-risk exposure history: Smoking, occupational exposures or other recognised risk factors.
Overview
Trucheck™ Intelli is a non-invasive blood test designed to screen for circulating tumour cells (CTCs) and tumour-associated cellular clusters linked to a wide range of solid malignancies. The test uses immunocytochemistry-based detection methods to identify abnormal cell populations that may be present in peripheral blood before clinical symptoms develop.
Detection of CTCs may indicate potential tumour activity and support earlier clinical investigation. The test is intended as a screening tool rather than a diagnostic method and positive findings require follow-up with conventional imaging, laboratory testing or specialist assessment.
Results are interpreted alongside clinical history, age-related risk factors, family history and other screening outcomes. Integrating this information may help guide decisions around monitoring intervals, referral pathways and broader preventive health strategies.
Practical
Specimen
Whole blood
Container
- 3 x EDTA tubes (purple colour cap) of 10 ml each
Volume
20 mL
Patient preparation
Not received blood transfusion at least 10 days prior to collection of the sample.
Not positive for HIV / HBV / HCV.
Research
- Akolkar, Dadasaheb, et al. "Circulating ensembles of tumor-associated cells: a redoubtable new systemic hallmark of cancer." International journal of cancer 146.12 (2020): 3485-3494.
- Ranade, Anantbhushan, et al. "Hallmark Circulating Tumor-Associated Cell Clusters Signify 230 Times Higher One-Year Cancer Risk." Cancer Prevention Research 14.1 (2021): 11-16.
- Gaya, Andrew, et al. "Evaluation of circulating tumor cell clusters for pan-cancer noninvasive diagnostic triaging." Cancer cytopathology 129.3 (2021): 226-238.