Women

• Cycle-related symptoms: PMS, mood changes or cycle irregularity.
• Menopausal transition: Menopause-related symptoms such as hot flushes or sleep disruption.
• Fatigue or low energy: Persistent tiredness or reduced stamina.
• Emotional wellbeing: Low mood or mood swings.
• Weight changes: Unexplained weight gain or changes in body composition.
• Hormone therapy context: Use of topical or transdermal hormone preparations.

Men

• Energy changes: Reduced stamina or persistent fatigue.
• Mood concerns: Low mood or reduced motivation.
• Sexual health: Reduced libido or changes in sexual interest.
• Stress-related symptoms: Difficulty coping with daily stress or disrupted sleep.
• Weight changes: Increased abdominal or overall body weight.
• Hormone therapy context: Use of topical or transdermal hormone preparations.

Overview

The Female/Male Saliva Profile III measures free, biologically active steroid hormones using saliva samples. The panel includes oestradiol, progesterone, testosterone, DHEA-S and cortisol measured at four time points across the day to assess diurnal patterns. Saliva sampling reflects the unbound fraction of hormones available to tissues at the time of collection.

This approach may be clinically useful when practitioners want insight into tissue-level hormone exposure rather than total circulating hormone levels. Measuring multiple sex hormones alongside diurnal cortisol allows patterns related to energy, mood, stress response and hormonal balance to be viewed together, particularly where topical or transdermal hormones are used.

Practitioners typically interpret results alongside symptom history, timing of sample collection, medication or hormone use, lifestyle factors and other laboratory findings. Attention is given to daily rhythm and individual context when reviewing patterns with clients.

Practical

Test type:

Hormonal: Steroid hormones

Sample required:

Saliva

Average processing time:

14 days